JG-231

Overview

JG-231 is an allosteric inhibitor of heat shock protein 70 ( Hsp70 ). JG - 231 inhibits the binding of Hsp70 and BAG family proteins, including inhibition of Hsp70 and BAG1 with a K i of 0.11 μM. JG-231 inhibits proliferation of tumor cells and induces apoptosis . JG-231 has antitumor activity.

Application

Products | Products > Disease Areas > Breast Cancer | Products > Disease Areas > Digestive System Inflammation | Products > Disease Areas > Cancer | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Digestive System Disease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > HSP | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-124611
• CAS No.: 1627126-59-3
• Molecular Formula: C22H18BrCl2N3OS4
• Molecular Weight: 619.47
• Purity: 98.47%
• Storage: 4°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Availability: In-stock

Source

Original product source