DB2313

Overview

DB2313 is a potent inhibitor of transcription factor PU.1 . DB2313 inhibits PU.1 -dependent reporter gene transactivation with an IC 50 of 5 μM. DB2313 disrupts the interaction of PU.1 with target gene promoters. DB2313 induces apoptosis in acute myeloid leukemia (AML) cells and has anticancer effects.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-124629
• CAS No.: 2170606-74-1
• Molecular Formula: C42H41FN8O2
• Molecular Weight: 708.83
• Purity: 99.48%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 3.33 mg/mL (4.70 mM); Clear solution
• Availability: In-stock

Source

Original product source