TBOPP is a selective inhibitor of DOCK1 with an IC 50 of 8.4 μM. TBOPP binds to the DOCK1 DHR-2 domain with high affinity ( K d of 7.1 μM), has anti-tumor activity for broader types of tumors.
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Signaling Pathways > DOCK
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