hSMG-1 inhibitor 11e

Overview

hSMG-1 inhibitor 11e is a potent and selective hSMG-1 kinase inhibitor with an IC 50 of <0.05 nM. hSMG-1 inhibitor 11e shows >900-fold selectivity over mTOR (IC 50 of 45 nM), PI3Kα/γ (IC 50 s of 61 nM and 92 nM) and CDK1/CDK2 (IC 50 s of 32 μM and 7.1 μM).

Application

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Product Information

• Catalog No.: HY-124760
• CAS No.: 1402452-10-1
• Molecular Formula: C26H27N7O3S
• Molecular Weight: 517.60
• Purity: 99.94%
• Storage: 4°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Solubility: ≥ 5 mg/mL (9.66 mM); Clear solution
• Availability: In-stock

Source

Original product source