Azaphilone-9 (AZA-9) is an inhibitor of HuR-ARE RNA interaction ( IC 50 =1.2 μM) by binding RNA-binding protein Hu antigen R ( HuR ). The HuR-RNA interactions stabilize many oncogenic mRNAs in tumors. Thus Azaphilone-9 potentially inhibit cancer cell growth and progression.
Products | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > HuR
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