FL118 (10,11-(Methylenedioxy)-20(S)-camptothecin), a Camptothecin ( HY-16560 ) analogue, is a potent and orally active survivin inhibitor. FL118 binds to oncoprotein DDX5 (p68) to dephosphorylates and degrades DDX5. FL118 can be used for the research of cancer .
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