PIK-C98

CAS No.：691388-62-2
Grade：99.98%
Formula：C16H10Cl2N2OS
M.W.：349.23

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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Overview

PIK-C98 is a potent and selective PI3K inhibitor, with IC 50 s of 0.59, 1.64, 3.65, and 0.74 μM for α , β , δ , and γ isoforms , respectively. PIK-C98 inhibits all class I PI3Ks but has no effects on AKT or mTOR activity. PIK-C98 interferes with the ATP-binding pockets of PI3Ks by forming H-bonds and arene-H interactions with specific amino acid residues. PIK-C98 induces apoptosis by inhibiting PI3K . PIK-C98 can be used for the research of multiple myeloma.

Application

Product Information

Catalog No.: HY-12491
CAS No.: 691388-62-2
Molecular Formula: C16H10Cl2N2OS
Molecular Weight: 349.23
Purity: 99.98%
Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source

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