Astemizole

Overview

Astemizole (R 43512), a second-generation antihistamine agent to diminish allergic symptoms with a long duration of action, is a histamine H1-receptor antagonist, with an IC 50 of 4 nM. Astemizole also shows potent hERG K + channel blocking activity with an IC 50 of 0.9 nM. Astemizole has antipruritic effects.

Application

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Product Information

• Catalog No.: HY-12532
• CAS No.: 68844-77-9
• Molecular Formula: C28H31FN4O
• Molecular Weight: 458.57
• Purity: 99.77%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 6.25 mg/mL (13.63 mM); Clear solution
• Availability: In-stock

Source

Original product source