PNU-282987

Overview

PNU-282987 is a potent α7 nicotinic acetylcholine receptor ( nAChR ) agonist with an EC 50 of 154 nM. PNU-282987 is also a functional antagonist of the 5-HT 3 receptor with an IC 50 of 4541 nM. PNU-282987 can be used for the research of central and peripheral nervous systems.

Application

Products | Products > Disease Areas > Parkinson's Disease | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Alzheimer's Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > nAChR | Products > Signaling Pathways > 5-HT Receptor

Product Information

• Catalog No.: HY-12560A
• CAS No.: 123464-89-1
• Molecular Formula: C14H18Cl2N2O
• Molecular Weight: 301.21
• Purity: 99.93%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 1 year; -20°C, 6 months (sealed storage, away from moisture)
• Solubility: 1 mg/mL (3.32 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source