Nexinhib20 is an inhibitor that targets the interactions of Rab27a-JFC1 ( IC 50 : 2.6 μM) and Rac-1-GTP . Nexinhib20 can inhibit neutrophil exocytosis, adhesion, and β2 integrin activation, and has anti-inflammatory activity. Nexinhib20 can be used in the research of diseases such as systemic inflammation and myocardial ischemia-reperfusion injury.
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