3-Oxo-5β-cholanoic acid

3-Oxo-5β-cholanoic acid
  • CAS No.:1553-56-6
  • Grade:99.62%
  • Formula:C24H38O3
  • M.W.:374.56
  • Solvent:≥ 2.5 mg/mL (6.67 mM); Clear solution

Overview

3-Oxo-5β-cholanoic acid (Dehydrolithocholic acid), a bile acid metabolite, inhibits the diferentiation of TH17 cells by directly binding to the key transcription factor RORγt ( K d =1.13 μM).

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Vitamin D Related/Nuclear Receptor | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > ROR

Product Information

  • Catalog No.: HY-125801
  • CAS No.: 1553-56-6
  • Molecular Formula: C24H38O3
  • Molecular Weight: 374.56
  • Purity: 99.62%
  • Storage: -20°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
  • Solubility: ≥ 2.5 mg/mL (6.67 mM); Clear solution
  • Availability: In-stock

Source

Original product source


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