Sigma-1 receptor antagonist 3

Overview

Sigma-1 receptor antagonist 3 (compound135) is a potent and selective Sigma-1 (σ1) receptor antagonist with a K i of 1.14 nM. Sigma-1 receptor antagonist 3 inhibits Human Ether-a-go-go-Related Gene (hERG) with an IC 50 of 1.54 μM. Sigma-1 receptor antagonist 3 has the potential for the neuropathic pain.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Pain | Products > Disease Areas > Alzheimer's Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Sigma Receptor | Products > Signaling Pathways > Potassium Channel

Product Information

• Catalog No.: HY-125820
• CAS No.: 1639220-17-9
• Molecular Formula: C19H23ClFN3O
• Molecular Weight: 363.86
• Purity: 99.47%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 1.25 mg/mL (3.44 mM); Clear solution
• Availability: In-stock

Source

Original product source