JNJ-26489112

Overview

JNJ-26489112, a CNS-active agent, exhibits broad-spectrum anticonvulsant activity in rodents against audiogenic, electrically-induced, and chemically-induced seizures. JNJ-26489112 inhibits voltage-gated Na + channels and N-type Ca 2+ channels , and is effective as a K + channel opener. JNJ-26489112 has very weak inhibition of CA-II (IC 50 =35 μM) and CA-I (18 μM).

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Calcium Channel | Products > Signaling Pathways > Sodium Channel | Products > Signaling Pathways > Potassium Channel

Product Information

• Catalog No.: HY-12596
• CAS No.: 871824-55-4
• Molecular Formula: C9H11ClN2O4S
• Molecular Weight: 278.71
• Purity: 99.31%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source