T3Inh-1

Overview

T3Inh-1 is a potent and selective inhibitor of ppGalNAc-T3 ( IC 50 =7 μM). T3Inh-1 reduces FGF23 hormone levels in both tissue cells and mice, without causing any toxic side effects. T3Inh-1 also prevents breast cancer cells. The enzyme ppGalNAc-T3 is implicated in at least two medically important pathways: cancer metastasis and stabilization of FGF23 (regulates phosphate levels in the bloodstream).

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Breast Cancer | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > FGFR | Products > Signaling Pathways > Glycosyltransferase

Product Information

• Catalog No.: HY-125961
• CAS No.: 50440-30-7
• Molecular Formula: C27H20N6O3
• Molecular Weight: 476.49
• Purity: 98.10%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 1 mg/mL (2.10 mM); Clear solution
• Availability: In-stock

Source

Original product source