SRI-29574 is an allosteric modulator of the dopamine transporter ( DAT ). SRI-29574 partially inhibits the uptake of the DAT ( IC 50 =2.3 nM) and also partially inhibits the uptake of the serotonin transporter ( SERT ) and norepinephrine transporter ( NET ). SRI-29574 may serve as a useful probe to study the function and regulatory mechanisms of DAT.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Dopamine Transporter | Products > Signaling Pathways > Serotonin Transporter
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