GNE-618

Overview

GNE-618 is a potent, orally active nicotinamide phosphoribosyl transferase ( NAMPT ) inhibitor with an IC 50 of 6 nM. GNE-618 depletes NAD levels and induces tumor cell death. Anti-tumor activity.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Lung Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > NAMPT

Product Information

• Catalog No.: HY-12628
• CAS No.: 1362151-42-5
• Molecular Formula: C21H15F3N4O3S
• Molecular Weight: 460.43
• Purity: 99.89%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.08 mg/mL (4.52 mM); Clear solution
• Availability: In-stock

Source

Original product source