CH-223191 is a potent and specific antagonist of aryl hydrocarbon receptor ( AhR ). CH-223191 inhibits TCDD-mediated nuclear translocation and DNA binding of AhR, and inhibits TCDD-induced luciferase activity with an IC 50 of 0.03 μM.
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Signaling Pathways > Aryl Hydrocarbon Receptor
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