RI(dl)-2 blocks RAD51 ’s D-loop activity in biochemical systems with an IC 50 value of 11.1 µM and inhibits homologous recombination ( HR ) activity with an IC 50 value of 3.0 µM. RI(dl)-2 inhibits HR -mediated repair of DNA double strand breaks and sensitizes different cancer cell lines.
Products | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > RAD51
Please leave a message for us or use the following ways to contact us, we will reply to you as soon as possible, and provide you with the most sincere service, thank you.