ARC 239 dihydrochloride

Overview

ARC 239 dihydrochloride is a selective α2B/2C adrenoceptor antagonist ( pK d values are 5.95, 7.41 and 7.56 at α2A, α2B, and α2C receptors respectively). ARC 239 dihydrochloride binds to CHO cell membranes expressing human recombinant a2A-, a2B- or a2C-adrenoceptor subtypes with pK i s of 5.6, 8.4, and 7.08, respectively.

Application

Products | Products > Disease Areas > Depression | Products > Disease Areas > Pain | Products > Disease Areas > Alzheimer's Disease | Products > Disease Areas > Hypertension | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Cardiovascular Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Adrenergic Receptor

Product Information

• Catalog No.: HY-12709A
• CAS No.: 55974-42-0
• Molecular Formula: C24H31Cl2N3O3
• Molecular Weight: 480.43
• Purity: 99.20%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.08 mg/mL (4.33 mM); Clear solution
• Availability: In-stock

Source

Original product source