Mofarotene

Overview

Mofarotene (Ro 40-8757), an arotinoid, is anticancer compound. Mofarotene induces apoptosis , associated with mitochondrial membrane depolarization, activation of caspase-3 and -9 , and enhanced production of reactive oxygen species . Mofarotene inhibits hematopoiesis in vitro by inhibiting maturation from primitive progenitor cells.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Reactive Oxygen Species (ROS) | Products > Signaling Pathways > Caspase

Product Information

• Catalog No.: HY-127149
• CAS No.: 125533-88-2
• Molecular Formula: C29H39NO2
• Molecular Weight: 433.63
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source