Thienopyridone is a potent and selective phosphatase of regenerating liver (PRL) phosphatase inhibitor with IC 50 s of 173 nM, 277 nM and 128 nM for PRL-1 , PRL-2 , and PRL-3 , respectively. Thienopyridone shows minimal effects on other phosphatases. Thienopyridone induces p130Cas cleavage and apoptosis and has anticancer effects.
Products | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Phosphatase | Products > Signaling Pathways > Apoptosis
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