AZ1136

AZ1136
  • CAS No.:1380508-60-0
  • Grade:99.98%
  • Formula:C24H21N5O3
  • M.W.:427.46

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

Overview

AZ1136 is a highly selective γ-secretase modulator ( GSM ). AZ1136 reduces the levels of Aβ42 and Aβ40 , with its IC 50 being 990 and 1400 nM. AZ1136 increases the levels of Aβ39 and Aβ37 , but does not affect Aβ38. AZ1136 can be used for the study of Alzheimer's disease.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Alzheimer's Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Stem Cell/Wnt | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > γ-secretase | Products > Signaling Pathways > Amyloid-β

Product Information

  • Catalog No.: HY-128391
  • CAS No.: 1380508-60-0
  • Molecular Formula: C24H21N5O3
  • Molecular Weight: 427.46
  • Purity: 99.98%
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
  • Availability: In-stock

Source

Original product source


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