SAG

Overview

SAG is a potent Smoothened ( Smo ) receptor agonist ( EC 50 =3 nM; K d =59 nM). SAG activates the Hedgehog signaling pathway and counteracts Cyclopamine ( HY-17024 ) inhibition of Smo .

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Pancreatic Cancer | Products > Disease Areas > Digestive System Cancer | Products > Signaling Pathways > Stem Cell/Wnt | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > Smo

Product Information

• Catalog No.: HY-12848
• CAS No.: 912545-86-9
• Molecular Formula: C28H28ClN3OS
• Molecular Weight: 490.06
• Purity: 99.60%
• Storage: 4°C, protect from light * In solvent : -80°C, 2 years; -20°C, 1 year (protect from light)
• Solubility: ≥ 5 mg/mL (10.20 mM); Clear solution
• Availability: In-stock

Source

Original product source