DNK-333 is a potent and balanced dual NK1 and NK2 receptor antagonist with IC 50 values of 4.8 nM and 5.5 nM, respectively. DNK-333 blocks the Neurokinin A (NKA) ( HY-P0197 )-induced bronchoconstriction in asthma.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Neurokinin Receptor
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