6-​Thioinosine

Overview

6-Thioinosine (6TI) is a purine antimetabolite and an anti-adipogenic agent. 6-Thioinosine reduces the mRNA levels of PPARγ and C/EBPα and downregulates the mRNA levels of PPARγ target genes (LPL, CD36, aP2, and LXRα ). 6-Thioinosine exerts its anti-adipogenic effects by downregulating PPARγ through JNK -dependent iNOS upregulation. 6-Thioinosine can be used to study adipocyte dysfunction.

Application

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Product Information

• Catalog No.: HY-128671
• CAS No.: 574-25-4
• Molecular Formula: C10H12N4O4S
• Molecular Weight: 284.30
• Purity: 99.31%
• Storage: -20°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Solubility: ≥ 2.08 mg/mL (7.32 mM); Clear solution
• Availability: In-stock

Source

Original product source