XPC-6444

Overview

XPC-6444 is a highly potent, isoform-selective, and CNS-penetrant Na V 1.6 inhibitor ( IC 50 =41 nM for hNa V 1.6). XPC-6444 also displays potent block of Na V 1.2 (IC 50 =125 nM). XPC-6444 shows anticonvulsant activity.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Sodium Channel

Product Information

• Catalog No.: HY-128772
• CAS No.: 2230144-21-3
• Molecular Formula: C22H25F3N4O2S2
• Molecular Weight: 498.58
• Purity: 98.93
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.08 mg/mL (4.17 mM); Clear solution
• Availability: In-stock

Source

Original product source