WEHI-9625

CAS No.：2595314-46-6
Grade：99.46%
Formula：C34H27NO5S2
M.W.：593.71
Solvent：2.5 mg/mL (4.21 mM); Suspended solution; Need ultrasonic

Important Notice

This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

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Overview

WEHI-9625 is a tricyclic sulfone, first-in-class inhibitor of apoptosis with an EC 50 of 69 nM. WEHI-9625 binds to VDAC2 and promotes its ability to inhibit apoptosis driven by mouse BAK . WEHI-9625 is completely inactive against both human BAK and the closely related apoptosis effector BAX .

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Signaling Pathways > VDAC | Products > Signaling Pathways > Apoptosis

Product Information

Catalog No.: HY-128777
CAS No.: 2595314-46-6
Molecular Formula: C34H27NO5S2
Molecular Weight: 593.71
Purity: 99.46%
Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
Solubility: 2.5 mg/mL (4.21 mM); Suspended solution; Need ultrasonic
Availability: In-stock

Source

Original product source

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