PF 05089771 tosylate is a potent, orally active and selective arylsulfonamide Na v 1.7 inhibitor, with IC 50 values of 11 nM, 12 nM, 13 nM, 171 nM and 8 nM for hNa v 1.7, cynNa v 1.7, dogNa v 1.7, ratNa v 1.7, and musNa v 1.7, respectively. PF 05089771 is under the study for pain and diabetic neuropathy.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Sodium Channel
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