Dexloxiglumide

Overview

Dexloxiglumide is an orally active and selective cholecystokinin type A ( CCKA ) receptor antagonist. Dexloxiglumide is the active enantiomer of Loxiglumide, inhibits smooth muscle cell contractions induced by cholecystokinin-octapeptide ( CCK-8 ). Dexloxiglumide exhibits moderate Caco-2 permeability that is polarized, concentration dependent, and pH dependent. Dexloxiglumide increases MRP1 -substrate fluorescein uptake. Dexloxiglumide can be studied in research for gastrointestinal diseases and tumors.

Application

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Product Information

• Catalog No.: HY-128878
• CAS No.: 119817-90-2
• Molecular Formula: C21H30Cl2N2O5
• Molecular Weight: 461.38
• Purity: 98.25%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: 2.5 mg/mL (5.42 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source