VP3.15

Overview

VP3.15 is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor, with IC 50 s of 1.59 μM and 0.88 μM for PDE7 and GSK-3 , respectively. VP3.15 has neuroprotective and neuroreparative activities, thus as potential combined anti-inflammatory and pro-remyelinating therapies for multiple sclerosis (MS).

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Phosphodiesterase (PDE) | Products > Signaling Pathways > GSK-3

Product Information

• Catalog No.: HY-128879
• CAS No.: 1281681-54-6
• Molecular Formula: C20H22N4OS
• Molecular Weight: 366.48
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source