SHMT-IN-2

Overview

SHMT-IN-2 is a stereo specific inhibitor of human SHMT1/2 with IC 50 values of 13 nM and 66 nM for SHMT1 and SHMT2, respectively. SHMT-IN-2 can block the growth of many human cancer cells, and has sensitivity for B-cell lymphomas.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Leukemia/Lymphoma/Myeloma | Products > Disease Areas > Blood Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Endocrinology | Products > Signaling Pathways > SHMT

Product Information

• Catalog No.: HY-129226
• CAS No.: 2102681-49-0
• Molecular Formula: C22H24F3N5O
• Molecular Weight: 431.45
• Purity: 99.60%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.5 mg/mL (5.79 mM); Clear solution
• Availability: In-stock

Source

Original product source