Pulrodemstat benzenesulfonate

Overview

Pulrodemstat (CC-90011) benzenesulfonate is a potent, selective, reversible and orally active inhibitor of lysine specific demethylase-1 (LSD1) with an IC 50 of 0.25 nM. Pulrodemstat benzenesulfonate is less enzymatic inhibition against LSD2, MAO-A , and MAO-B . Pulrodemstat benzenesulfonate induces acute myeloid leukemia (AML) and small cell lung cancer (SCLC) cells differentiation and has potent anticancer activity.

Application

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Product Information

• Catalog No.: HY-129388B
• CAS No.: 2097523-60-7
• Molecular Formula: C30H29F2N5O5S
• Molecular Weight: 609.64
• Purity: 99.64%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 2 years; -20°C, 1 year (sealed storage, away from moisture)
• Solubility: ≥ 2.08 mg/mL (3.41 mM); Clear solution
• Availability: In-stock

Source

Original product source