GNF4877

Overview

GNF4877 is a potent DYRK1A and GSK3β inhibitor with IC 50 s of 6 nM and 16 nM, respectively, which leads to blockade of nuclear factor of activated T-cells (NFATc) nuclear export and increased β-cell proliferation ( EC 50 of 0.66 μM for mouse β (R7T1) cells).

Application

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Product Information

• Catalog No.: HY-129492
• CAS No.: 2041073-22-5
• Molecular Formula: C25H27FN6O4
• Molecular Weight: 494.52
• Purity: 99.82%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source