Cabozantinib-d 6 is the deuterium labeled Cabozantinib. Cabozantinib is a potent multiple receptor tyrosine kinases (RTKs) inhibitor that inhibits VEGFR2, c-Met, Kit, Axl and Flt3 with IC 50 s of 0.035, 1.3, 4.6, 7 and 11.3 nM, respectively.
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > VEGFR | Products > Signaling Pathways > c-Met/HGFR | Products > Signaling Pathways > c-Kit | Products > Signaling Pathways > TAM Receptor | Products > Signaling Pathways > FLT3 | Products > Signaling Pathways > Apoptosis
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