LC3-mHTT-IN-AN1

LC3-mHTT-IN-AN1
  • CAS No.:486443-73-6
  • Grade:98.86%
  • Formula:C15H9Br2NO3
  • M.W.:411.04
  • Solvent:≥ 2.08 mg/mL (5.06 mM); Clear solution

Overview

LC3-mHTT-IN-AN1 (Compound AN1) is a mHTT-LC3 linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. LC3-mHTT-IN-AN1 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Autophagy | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Atg8/LC3 | Products > Signaling Pathways > Autophagy

Product Information

  • Catalog No.: HY-130258
  • CAS No.: 486443-73-6
  • Molecular Formula: C15H9Br2NO3
  • Molecular Weight: 411.04
  • Purity: 98.86%
  • Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
  • Solubility: ≥ 2.08 mg/mL (5.06 mM); Clear solution
  • Availability: In-stock

Source

Original product source


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