7-Hydroxymethotrexate

Overview

7-Hydroxymethotrexate is a major metabolite of Methotrexate ( HY-14519 ). Methotrexate , an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase , thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Drug Metabolite

Product Information

• Catalog No.: HY-130569
• CAS No.: 5939-37-7
• Molecular Formula: C20H22N8O6
• Molecular Weight: 470.44
• Purity: 98.14%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source