Mutated EGFR-IN-3

Overview

Mutated EGFR-IN-3 (compound 3) is a potent, ATP-competitive and highly selective allosteric dibenzodiazepinone inhibitor of the EGFR (L858R/T790M) and EGFR (L858R/T790M/C797S) mutants with IC 50 values of 12 nM and 13 nM, respectively.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > EGFR

Product Information

• Catalog No.: HY-130608
• CAS No.: 2375107-27-8
• Molecular Formula: C31H29FN4O2
• Molecular Weight: 508.59
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source