c-Fms-IN-3

Overview

c-Fms-IN-3 is an orally active c-Fms ( CSF1R ) kinase inhibitor ( IC 50 = 0. 8 nM). c-Fms-IN-3 inhibits CSF1R kinase activity and reduces macrophage populations. c-Fms-IN-3 reduces bone erosion, pannus invasion, cartilage damage, and inflammation in collagen ( HY-NP003 )-induced arthritis mouse model. c-Fms-IN-3 is useful for arthritis research.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Liver Cancer | Products > Disease Areas > Digestive System Cancer | Products > Disease Areas > Leukemia/Lymphoma/Myeloma | Products > Disease Areas > Blood Disease | Products > Disease Areas > Cancer | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > c-Fms | Products > Signaling Pathways > Trk Receptor | Products > Signaling Pathways > c-Kit | Products > Signaling Pathways > TAM Receptor | Products > Signaling Pathways > FLT3

Product Information

• Catalog No.: HY-13075
• CAS No.: 885704-21-2
• Molecular Formula: C23H30N6O
• Molecular Weight: 406.52
• Purity: 98.83%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (6.15 mM); Clear solution
• Availability: In-stock

Source

Original product source