MAO-IN-M30 dihydrochloride is an orally active, brain-permeable, and brain selective irreversible MAO-A ( IC 50 =37 nM) and MAO-B ( IC 50 =57 nM) inhibitor. MAO-IN-M30 dihydrochloride is a potent iron chelator and radical scavenger . MAO-IN-M30 dihydrochloride has a neuroprotective effect against Dexamethasone-induced brain cell apoptosis . MAO-IN-M30 dihydrochloride also exhibits neurorestorative activity in post MPTP and lactacystin models of Parkinson's disease. MAO-IN-M30 (dihydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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