HPK1-IN-2 dihydrochloride is an orally active HPK1 inhibitor ( IC 50 < 0.05 µM) with antitumor activity. HPK1-IN-2 dihydrochloride inhibits the activity of Lck ( IC 50 < 0.05 µM) and Flt3 ( IC 50 < 0.05 µM) kinases.
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > MAP4K | Products > Signaling Pathways > FLT3 | Products > Signaling Pathways > Src
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