VEGFR-3-IN-1

Overview

VEGFR-3-IN-1 is a potent and selective VEGFR3 inhibitor with an IC 50 of 110.4 nM. VEGFR-3-IN-1 significantly inhibits proliferation and migration of VEGF-C-induced human dermal lymphatic endothelial cells (HDLEC), MDA-MB-231, and MDA-MB-436 cells by inactivating the VEGFR3 signaling pathway, and also effectively inhibits breast cancer growth.

Application

Products | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > VEGFR

Product Information

• Catalog No.: HY-132305
• CAS No.: 2756668-73-0
• Molecular Formula: C29H29ClF3N7OS
• Molecular Weight: 616.10
• Purity: 98.76%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 1.25 mg/mL (2.03 mM); Clear solution
• Availability: In-stock

Source

Original product source