Englerin A

Overview

Englerin A is a potent and selective activator of TRPC4 and TRPC5 channels, with EC 50 s of 11.2 and 7.6 nM, respectively. Englerin A can induce renal carcinoma cells death by elevated Ca 2+ influx and Ca 2+ cell overload.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > TRP Channel

Product Information

• Catalog No.: HY-133168
• CAS No.: 1094250-15-3
• Molecular Formula: C26H34O6
• Molecular Weight: 442.54
• Purity: 99.43%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 1.25 mg/mL (2.82 mM); Clear solution
• Availability: In-stock

Source

Original product source