Methotrexate α-tert-butyl ester

Overview

Methotrexate α-tert-butyl ester, capped by OtBu, significantly reduces tumor growth in HT1080 tumor bearing mice. Methotrexate is an antimetabolite and antifolate agent and is also an immunosuppressant and antineoplastic agent.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Antifolate | Products > Signaling Pathways > DNA/RNA Synthesis

Product Information

• Catalog No.: HY-133887
• CAS No.: 79640-70-3
• Molecular Formula: C24H30N8O5
• Molecular Weight: 510.55
• Purity: 97.38%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (4.90 mM); Clear solution
• Availability: In-stock

Source

Original product source