Emodic acid (NSC624610) is an anthraquinone compound isolated from A. microcarpus , which can inhibit the proliferation of cancer cells by inhibiting the activity of NF-κB . Emodic acid can also inhibit the phosphorylation of p38 , ERK and JNK , the secretion of tumor-promoting cytokines IL-1β and IL-6 , and the expression of VEGF and MMP , thereby inhibiting the invasion and migration potential of cancer cells.
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