Avatrombopag maleate

Overview

Avatrombopag (AKR-501) maleate is an orally active, non-peptide thrombopoietin receptor ( TPO receptor ) agonist ( EC 50 : 3.3 nM). Avatrombopag maleate mimics the biological activity of TPO. Avatrombopag maleate increases platelet production by activating intracellular signaling systems and promotes the production of platelets and megakaryocytes from hematopoietic precursor cells. Avatrombopag maleate is a substrate for cytochrome P450 (CYP) 2C9 and CYP3A .

Application

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Product Information

• Catalog No.: HY-13463A
• CAS No.: 677007-74-8
• Molecular Formula: C33H38Cl2N6O7S2
• Molecular Weight: 765.73
• Purity: 99.99%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source