OMDM-6 is a hybrid agonist of vanilloid receptor type 1 (VR1, TRPV1) ( EC 50 =75 nM) and cannabinoid receptor type 1 ( CB1 ) ( K i =3.2 μM). OMDM-6 inhibits anandamide cellular uptake (ACU) with a K i of 7.0 μM.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > TRP Channel | Products > Signaling Pathways > Cannabinoid Receptor | Products > Signaling Pathways > Endogenous Metabolite
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