GP-82996 (CINK4) is a pharmacological inhibitor of CDK4/6 . GP-82996 has IC 50 s of 1.5, 5.6 and 25 μM for CDK4/cyclin D1, CDK6/cyclin D1 and Cdk5/p35, respectively. GP-82996 induces the apoptosis of cancer cells U2OS. GP-82996 can be used in the research of cancer .
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