Multitarget AD inhibitor-1

Overview

Multitarget AD inhibitor-1 is a selective and reversible butyrylcholinesterase (BuChE) inhibitor with IC 50 s of 7.22 μM and 1.55 μM for hBuChE and eqBuChE (BuChE from equine serum), respectively. Multitarget AD inhibitor-1 inhibits β-secretase ( IC 50hBACE-1 =41.60 μM), amyloid β aggregation ( IC 50Aβ =3.09 μM), tau aggregation. Multitarget AD inhibitor-1, a diphenylpropylamine derivative, has the potential for multifunctional disease-modifying anti-Alzheimer’s research.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Beta-secretase | Products > Signaling Pathways > Amyloid-β | Products > Signaling Pathways > Cholinesterase (ChE)

Product Information

• Catalog No.: HY-136813
• CAS No.: 2205015-77-4
• Molecular Formula: C29H38N2O
• Molecular Weight: 430.62
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source