TEAD-IN-1 (Compound 2) is potent TEAD autopalmitoylation inhibitor, with an IC 50 of 603 nM. TEAD-IN-1 increases the interaction of TEAD and VGLL4. TEAD-IN-1 decreases the interaction of YAP and TEAD . TEAD-IN-1 can be used for the research of cancer .
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