Zelpolib is a non-competitive Pol δ inhibitor. Zelpolib shows robust inhibition of Pol δ activity against dTTP with a K i of 4.3 μM. Zelpolib inhibits cellular DNA replication . Zelpolib shows antiproliferative properties.
Products | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > DNA/RNA Synthesis
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